WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID.
The second row lists the following statistics:
Finally, genes in the pathway are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:KEGG pathway       Name:Long-term potentiation       ID:04720
C=70; O=3; E=0.09; R=33.61; rawP=0.0001; adjP=0.0017
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000151067 NA CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 775 ENSG00000151067


Database:KEGG pathway       Name:Cell cycle       ID:04110
C=124; O=3; E=0.16; R=18.97; rawP=0.0005; adjP=0.0043
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000072501 NA SMC1A structural maintenance of chromosomes 1A 8243 ENSG00000072501


Database:KEGG pathway       Name:Wnt signaling pathway       ID:04310
C=150; O=3; E=0.19; R=15.68; rawP=0.0009; adjP=0.0051
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000100888 NA CHD8 chromodomain helicase DNA binding protein 8 57680 ENSG00000100888


Database:KEGG pathway       Name:Notch signaling pathway       ID:04330
C=47; O=2; E=0.06; R=33.37; rawP=0.0017; adjP=0.0058
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393


Database:KEGG pathway       Name:Huntington's disease       ID:05016
C=183; O=3; E=0.23; R=12.85; rawP=0.0017; adjP=0.0058
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393
3  ENSG00000197386 NA HTT huntingtin 3064 ENSG00000197386


Database:KEGG pathway       Name:Cytosolic DNA-sensing pathway       ID:04623
C=56; O=2; E=0.07; R=28.00; rawP=0.0024; adjP=0.0068
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000088888 NA MAVS mitochondrial antiviral signaling protein 57506 ENSG00000088888
2  ENSG00000148606 NA POLR3A polymerase (RNA) III (DNA directed) polypeptide A, 155kDa 11128 ENSG00000148606


Database:KEGG pathway       Name:Adherens junction       ID:04520
C=73; O=2; E=0.09; R=21.48; rawP=0.0040; adjP=0.0085
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393


Database:KEGG pathway       Name:Renal cell carcinoma       ID:05211
C=70; O=2; E=0.09; R=22.40; rawP=0.0036; adjP=0.0085
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393


Database:KEGG pathway       Name:TGF-beta signaling pathway       ID:04350
C=84; O=2; E=0.11; R=18.67; rawP=0.0052; adjP=0.0098
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393


Database:KEGG pathway       Name:Prostate cancer       ID:05215
C=89; O=2; E=0.11; R=17.62; rawP=0.0058; adjP=0.0099
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000005339 NA CREBBP CREB binding protein 1387 ENSG00000005339
2  ENSG00000100393 NA EP300 E1A binding protein p300 2033 ENSG00000100393




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).